Tramadol can slow or stop your breathing, especially when you begin applying this medicine or as soon as your dose is changed. Never take Tramadol in larger amounts, and longer than prescribed. Do not crush, break, or open an extended-release pill. Swallow it whole to prevent contact with a potentially terminal dose.

Children younger than 12 shouldn’t take tramadol, according to 2017 rules from the Food and Drug Administration (FDA). “Our decision today was developed based on the latest evidence sufficient reason for this goal in mind: keeping our little ones safe,” Dr. Douglas Throckmorton, deputy center director for regulatory programs at the FDA’s Center for Drug Evaluation and Research, said in the statement.